Characterization and antivirus activities of a novel bovine IFN-omega24

X Luo, Y Guo, J Bao, Y Liu, D An, B Ma, M Gao… - Molecular …, 2015 - Elsevier
activities was detected. In this study, we identified and characterized this novel gene and
named BoIFN-ω24 according to its position in the bovine genome (Zhao et al., 2009). Biological …

Characterization and antivirus activities of a novel bovine IFN-omega24.

LXX Luo XiuXin, GYL Guo YongLi, BJ Bao Jun… - 2015 - cabidigitallibrary.org
… according to its position in the bovine genome. In this study, the … antiviral or antiproliferation
activity was determined in vitro. Results showed that BoIFN-ω24 exhibits high antiviral activity

Molecular characterization and biological activity of bovine interferon-omega3

D An, Y Guo, J Bao, X Luo, Y Liu, B Ma, M Gao… - Research in veterinary …, 2017 - Elsevier
… a potential as a novel antiviral therapeutic agent, exerts antiviral activity against VSV in …
against bovine virus that including BEV, IBRV and BVDV. In this study, we present a novel type I …

Interferon-omega: Current status in clinical applications

S Li, F Zhao, J Shao, Y Xie, H Chang… - International …, 2017 - Elsevier
… We provide a broad knowledge of the characteristics and biological functions of IFN-ω. …
antiviral activities after being treated with 0.25% trypsin. However, it retains high antiviral activity

Design, biological activity and signaling pathway of bovine consensus omega interferon expressed in Pichia pastoris

M Gao, Y Guo, X Luo, J Du, Y Wang, C Cao… - Molecular …, 2019 - Elsevier
… Therefore, a consensus BoIFN-ω (CoBoIFN-ω) was designed and characterized in this
study, and was demonstrated to have antiviral and antiproliferative activities, transduce signals …

Characterization and signaling pathway analysis of interferon-kappa in bovine

Y Guo, D An, Y Liu, J Bao, X Luo, X Cheng… - Developmental & …, 2017 - Elsevier
… This study reported the identification and characterization of bovine IFN-κ, including its
antiviral activity and signaling pathway. BoIFN-ε and BoIFN-β contain a signal peptide of 21 …

[HTML][HTML] Cloning, prokaryotic soluble expression, and analysis of antiviral activity of two novel feline IFN-ω proteins

X Wang, F Li, M Han, S Jia, L Wang, X Qiao, Y Jiang… - Viruses, 2020 - mdpi.com
activity in Vero, F81 (feline kidney cell), Madin–Darby bovine … -species antiviral activity than
the INTERCAT IFN antiviral drug… Homology and phylogenetic tree analysis of the feline IFN-ω …

[HTML][HTML] A novel type-I interferon family, bovine interferon-chi, is involved in positive-feedback regulation of interferon production

Y Guo, Z Song, C Li, Y Yu, H Dai, X Luo… - Frontiers in …, 2020 - frontiersin.org
… on the bovine genome (5). Here, we characterize and measure the activity and regulation of
… have the typical molecular characteristics of type-I IFNs; exhibit antiviral and antiproliferative …

[HTML][HTML] Cross-species genome-wide analysis reveals molecular and functional diversity of the unconventional interferon-ω subtype

LE Shields, J Jennings, Q Liu, J Lee, W Ma… - Frontiers in …, 2019 - frontiersin.org
… their antiviral and inflammatory regulation, we characterized … -ω subtype has evolved several
novel features, which include: … that have much higher antiviral potency than typical IFN-α (14…

Identification and characterization of a rabbit novel IFN-α unlocated in genome

M Gao, Y Liu, Y Guo, Y Wang, H Dai, Z Song… - Developmental & …, 2018 - Elsevier
… A novel rabbit IFN-α gene named RbIFN-αNov1 was amplified from rabbit genomic …
characterized in this study. Our results showed that RbIFN-αNov1 exhibits significant antiviral activity